CD43 anticorps (AA 272-400)

N° du produit ABIN7873162

Cet anticorps anti-CD43 Monoclonal Souris (Clone 4I3) (ABIN7873162) détecte spécifiquement CD43 dans FACS, WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CD43 anticorps (AA 272-400) (ABIN7873162)

Antigène: CD43 (SPN) (Sialophorin (SPN))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD43 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 4I3

Détail du produit anti-CD43 anticorps

Épitope: AA 272-400

Fonction: CD43 Antibody

Purification: Affinity purified

Immunogène: A human recombinant protein (amino acids A272-P400) was used as the immunogen for the CD43 antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the CD43 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the CD43 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur CD43

Antigène: CD43 (SPN) (Sialophorin (SPN))

Autre désignation: CD43

Sujet: CD43, also known as leukosialin or sialophorin, is a transmembrane cell surface protein that in humans is encoded by the SPN gene. It is mapped to 16p11.2. It is a major sialoglycoprotein on the surface of human T lymphocytes, monocytes, granulocytes, and some B lymphocytes, which is important for immune function and may be part of a physiologic ligand-receptor complex involved in T-cell activation. Expression of CD43 is deficient and/or defective in the X-chromosome-linked immunodeficiency disorder Wiscott-Aldrich syndrome, suggesting that CD43 have a role in T-cell activation. T-cell activation requires the removal of CD43 from the immunologic synapse to allow efficient engagement of the TCR with molecules on the APC.

UniProt: P16150

Pathways: Regulation of Leukocyte Mediated Immunity