FTO anticorps (AA 279-505)
Aperçu rapide pour FTO anticorps (AA 279-505) (ABIN7873222)
Antigène
Voir toutes FTO AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 279-505
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Fonction
- FTO Antibody / Fat mass and obesity associated
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Purification
- Affinity purified
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Immunogène
- An E. coli-derived human protein (amino acids D279-P505) was used as the immunogen for the FTO antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the FTO antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the FTO antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- FTO (Fat Mass and Obesity-Associated (FTO))
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Autre désignation
- FTO
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Sujet
- Fat mass and obesity-associated protein also known as alpha-ketoglutarate-dependent dioxygenase FTO is an enzyme that in humans is encoded by the FTO gene located on chromosome 16. This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.
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UniProt
- Q9C0B1
Antigène
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