Ki-67 anticorps (AA 2860-3256)

N° du produit ABIN7873320

L’anticorps anti-Ki-67 Monoclonal Souris est utilisé pour la détection de Ki-67 dans des échantillons de Humain. Il a été validé pour WB, FACS, IF et IHC (p).

Aperçu rapide pour Ki-67 anticorps (AA 2860-3256) (ABIN7873320)

Antigène: Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Ki-67 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 5C7

Détail du produit anti-Ki-67 anticorps

Épitope: AA 2860-3256

Fonction: Ki67 Antibody

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids K2860-I3256) was used as the immunogen for the Ki67 antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the Ki67 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Ki67 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Ki-67

Antigène: Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))

Autre désignation: Ki67

Sujet: Ki-67 (Proliferation-related Ki-67 antigen), also known as MKI67 or KIA, is a protein that in humans is encoded by the MKI67 gene. From study of a panel of human-rodent somatic cell hybrids, it has been demonstrated that a gene involved in the expression of the MKI67 antigen is located on chromosome 10. By in situ hybridization, Fonatsch et al. (1991) regionalized the MKI67 gene to chromosome 10q25-qter. By FISH, Traut et al. (1998) mapped the mouse Mki67 gene to chromosome 7F3-F5. Antigen KI-67 is a nuclear protein that is associated with and may be necessary for cellular proliferation. Furthermore it is associated with ribosomal RNA transcription. Inactivation of antigen KI-67 leads to inhibition of ribosomal RNA synthesis.

UniProt: P46013

Pathways: Glycosaminoglycan Metabolic Process