GPR81
Reactivité: Humain, Souris, Rat
WB, ELISA, IHC
Hôte: Lapin
Polyclonal
Biotin
Indications d'application
The stated application concentrations are suggested starting points. Titration of the HCAR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Aliquot the HCAR1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Antigène
GPR81
(G Protein-Coupled Receptor 81 (GPR81))
Autre désignation
HCAR1
Sujet
HCAR1 is a G-protein coupled receptor that is primarily found in various tissues throughout the body, including the liver, adipose tissue, and skeletal muscle. When activated by its ligand, which in this case is a specific type of hydroxycarboxylic acid, HCAR1 plays a key role in regulating glucose and lipid metabolism. One of the most intriguing aspects of HCAR1 is its ability to promote the use of fats as an energy source, a process known as fatty acid oxidation. By activating HCAR1, the body is able to break down fatty acids more efficiently, leading to improved metabolic health and potentially aiding in weight management. Additionally, HCAR1 has been shown to have anti-inflammatory effects, which can help combat chronic inflammation associated with metabolic disorders such as obesity and diabetes. By modulating the body's immune response, HCAR1 can help reduce inflammation and improve overall health.