Gephyrin anticorps (AA 288-735)
Aperçu rapide pour Gephyrin anticorps (AA 288-735) (ABIN7873329)
Antigène
Voir toutes Gephyrin (GPHN) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 288-735
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Fonction
- Zebrafish Gephyrin Antibody / Gphna / Gphnb
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Purification
- Antigen affinity chromatography
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Immunogène
- An E.coli-derived zebrafish GPHNa/b recombinant protein (amino acids V288-L735) was used as the immunogen for the Zebrafish Gephyrin antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Optimal dilution of the Zebrafish Gephyrin antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the Zebrafish Gephyrin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Gephyrin (GPHN)
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Autre désignation
- Gephyrin
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Sujet
- Gephyrin is a protein that in humans is encoded by the GPHN gene. This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described, however, the full-length nature of all transcript variants is not currently known.
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UniProt
- D3KYK7
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Pathways
- Synaptic Membrane, Skeletal Muscle Fiber Development
Antigène
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