Recombinant RBP4 anticorps (AA 29-148)

N° du produit ABIN7873344

L’anticorps anti-RBP4 Monoclonal Lapin est utilisé pour la détection de RBP4 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour Recombinant RBP4 anticorps (AA 29-148) (ABIN7873344)

Antigène: RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp RBP4 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: RBP4-7045R

Détail du produit anti-RBP4 anticorps

Épitope: AA 29-148

Fonction: Recombinant Retinol Binding Protein 4 Antibody / RBP4 (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: A portion of amino acids 29-148 was used as the immunogen for the recombinant Retinol Binding Protein 4 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the recombinant Retinol Binding Protein 4 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Aliquot the recombinant Retinol Binding Protein 4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur RBP4

Antigène: RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

Autre désignation: Retinol Binding Protein 4

Sujet: Retinol (Vitamin A) is transported in the blood bound to its carrier protein, retinol-binding protein (RBP), also designated plasma retinol-binding protein (PRBP) or RBP4. A member of the lipocalin family, RBP conveys retinol from stores in the liver to peripheral tissues. In plasma, RBP binds transthyretin (TTR, formerly called prealbumin) to prevent glomerular filtration of low molecular weight RBP in the kidneys. The stability of this complex holds diagnostic importance because the molar ratio of RBP:TTR provides an indirect way to indicate marginal Vitamin A deficiency. Vitamin A deficiency blocks the secretion of RBP, resulting in defective delivery and supply to epidermal cells. Originally identified solely as a transporter protein, recent studies correlating increased levels of RBP expression in adipose tissue with Insulin resistance have generated research into the possible roles the protein may play in the pathogenesis of type 2 diabetes and obesity.

UniProt: P02753

Pathways: Regulatory RNA Pathways, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response