CD276 anticorps (AA 7-3, AA 29-458)

N° du produit ABIN7873425

L’anticorps anti-CD276 Polyclonal Lapin est utilisé pour la détection de CD276 dans des échantillons de Humain. Il a été validé pour WB, ELISA, FACS et IHC (p).

Aperçu rapide pour CD276 anticorps (AA 7-3, AA 29-458) (ABIN7873425)

Antigène: CD276

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD276 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CD276 anticorps

Épitope: AA 7-3, AA 29-458

Fonction: B7-H3 Antibody / CD276

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids L29-Q458) was used as the immunogen for the B7-H3 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the B7-H3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the B7-H3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur CD276

Antigène: CD276

Autre désignation: B7-H3

Sujet: Cluster of Differentiation 276 (CD276) or B7 Homolog 3 (B7-H3) is a human protein encoded by the CD276 gene. The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UniProt: Q5ZPR3

Pathways: Cancer Immune Checkpoints