Haptoglobin anticorps (AA 296-322)

N° du produit ABIN7873465

Cet anticorps anti-Haptoglobin Polyclonal Lapin (ABIN7873465) détecte spécifiquement Haptoglobin dans WB, FACS, IHC (p) et IF. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour Haptoglobin anticorps (AA 296-322) (ABIN7873465)

Antigène: Haptoglobin (HP)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Haptoglobin est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-Haptoglobin anticorps

Épitope: AA 296-322

Fonction: Haptoglobin Antibody / HP

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 296-322 from the human protein was used as the immunogen for the Haptoglobin antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the Haptoglobin antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Haptoglobin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Haptoglobin

Antigène: Haptoglobin (HP)

Autre désignation: Haptoglobin

Sujet: This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: P00738

Pathways: Transition Metal Ion Homeostasis