LIN28A anticorps (AA 3-209)

N° du produit ABIN7873524

L’anticorps anti-LIN28A Polyclonal Lapin est utilisé pour la détection de LIN28A dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IF, FACS et IHC (p).

Aperçu rapide pour LIN28A anticorps (AA 3-209) (ABIN7873524)

Antigène: LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LIN28A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-LIN28A anticorps

Épitope: AA 3-209

Fonction: LIN28A Antibody / Lin28

Purification: Affinity purified

Immunogène: Recombinant human protein (amino acids S3-N209) was used as the immunogen for the LIN28A antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the LIN28A antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the LIN28A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur LIN28A

Antigène: LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))

Autre désignation: LIN28A

Sujet: Protein lin-28 homolog A is a protein that in humans is encoded by the LIN28A gene. It is mapped to 1p36.11. This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues.

UniProt: Q9H9Z2

Pathways: Stem Cell Maintenance