BCR anticorps (AA 3-264)

N° du produit ABIN7873528

Cet anticorps anti-BCR Polyclonal Lapin (ABIN7873528) détecte spécifiquement BCR dans WB, ELISA et FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour BCR anticorps (AA 3-264) (ABIN7873528)

Antigène: BCR (Breakpoint Cluster Region (BCR))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCR est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-BCR anticorps

Épitope: AA 3-264

Fonction: Breakpoint cluster region protein Antibody / BCR

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids D3-N264) was used as the immunogen for the Breakpoint cluster region protein antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Breakpoint cluster region protein antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Breakpoint cluster region protein antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur BCR

Antigène: BCR (Breakpoint Cluster Region (BCR))

Autre désignation: Breakpoint cluster region protein

Sujet: The breakpoint cluster region protein (BCR) is a protein that in humans is encoded by the BCR gene. A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.

UniProt: P11274

Pathways: Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling