GPX4 anticorps (AA 30-197)

N° du produit ABIN7873574

Cet anticorps Souris Monoclonal détecte spécifiquement GPX4 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour GPX4 anticorps (AA 30-197) (ABIN7873574)

Antigène: GPX4 (Glutathione Peroxidase 4 (GPX4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GPX4 est non-conjugé

Application: Western Blotting (WB)

Clone: 6I4E7

Détail du produit anti-GPX4 anticorps

Épitope: AA 30-197

Fonction: Glutathione Peroxidase 4 Antibody / GPX4

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids A30-F197) was used as the immunogen for the Glutathione Peroxidase 4 antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the Glutathione Peroxidase 4 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Glutathione Peroxidase 4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur GPX4

Antigène: GPX4 (Glutathione Peroxidase 4 (GPX4))

Autre désignation: Glutathione Peroxidase 4

Sujet: Glutathione peroxidase 4, also known as GPX4, is an enzyme that in humans is encoded by the GPX4 gene. This gene encodes a member of the glutathione peroxidase protein family. Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. The encoded protein has been identified as a moonlighting protein based on its ability to serve dual functions as a peroxidase as well as a structural protein in mature spermatozoa. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified. Alternative splicing results in multiple transcript variants.

UniProt: P36969