HTRA2 anticorps (AA 30-458)

N° du produit ABIN7873586

Cet anticorps Lapin Polyclonal détecte spécifiquement HTRA2 dans WB, ELISA, IF, IHC (p) et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour HTRA2 anticorps (AA 30-458) (ABIN7873586)

Antigène: HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HTRA2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-HTRA2 anticorps

Épitope: AA 30-458

Fonction: OMI Antibody / HTRA2

Purification: Antigen affinity chromatography

Immunogène: An E.coli-derived human recombinant protein (amino acids R30-E458) was used as the immunogen for the OMI antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the OMI antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the OMI Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur HTRA2

Antigène: HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

Autre désignation: OMI

Sujet: Serine protease HTRA2, mitochondrial, also called Omi stress-regulated endoprotease (OMI), is an enzyme that in humans is encoded by the HTRA2 gene. This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.

UniProt: O43464

Pathways: Positive Regulation of Endopeptidase Activity