ENPP3 anticorps (AA 300-600)

N° du produit ABIN7873683

L’anticorps anti-ENPP3 Monoclonal Souris est utilisé pour la détection de ENPP3 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour ENPP3 anticorps (AA 300-600) (ABIN7873683)

Antigène: ENPP3 (Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ENPP3 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: ENPP3-9892

Détail du produit anti-ENPP3 anticorps

Épitope: AA 300-600

Fonction: CD203c Antibody / ENPP3 / PD-Ibeta / PDNP3

Purification: Protein A/G affinity

Immunogène: A portion of amino acids 300-600 from human ENPP3 protein was used as the immunogen for the CD203c antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the CD203c antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the CD203c antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur ENPP3

Antigène: ENPP3 (Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3))

Autre désignation: CD203c

Sujet: Ecto-nucleotide pyrophosphatase/phosphodiesterase-I enzymes (E-NPP), a group of type II transmembrane proteins, cleave phosphodiester and phosphosulfate bonds in deoxynucleotides, NAD, and nucleotide sugars. There exist three closely related proteins in mammalian species: E-NPP1 (PC-1), E-NPP2 (PDNP2), and E-NPP-3, also known as CD203c, each expressed in different cells or at different locations in the same cells. Basophils, a type of major proinflammatory effector cells involved in diverse pathologic reactions, exhibit CD203c expression. For instance, CD203c expression increases in response to a variety of allergens, including cat dander, latex, and bee and wasp venom. However, these allergies are not the only condition associated with CD203c upregulation, CD203c upregulation may also serve as a tumor marker for colon carcinoma.

UniProt: O14638

Pathways: Regulation of Muscle Cell Differentiation, Negative Regulation of Transporter Activity