SAP130 anticorps (AA 309-913)

N° du produit ABIN7873743

L’anticorps anti-SAP130 Polyclonal Lapin est utilisé pour la détection de SAP130 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IHC (p), IF et FACS.

Aperçu rapide pour SAP130 anticorps (AA 309-913) (ABIN7873743)

Antigène: SAP130 (Sin3A-Associated Protein, 130kDa (SAP130))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SAP130 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-SAP130 anticorps

Épitope: AA 309-913

Fonction: SAP130 Antibody / Sin3-associated polypeptide p130

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids H309-H913) was used as the immunogen for the SAP130 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the SAP130 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the SAP130 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur SAP130

Antigène: SAP130 (Sin3A-Associated Protein, 130kDa (SAP130))

Autre désignation: SAP130

Sujet: Histone deacetylase complex subunit SAP130 is an enzyme that in humans is encoded by the SAP130 gene. This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.

UniProt: Q9H0E3