LYPD3 anticorps (AA 31-245)

N° du produit ABIN7873757

Cet anticorps Lapin Polyclonal détecte spécifiquement LYPD3 dans ELISA, WB, IHC (p), IF et FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour LYPD3 anticorps (AA 31-245) (ABIN7873757)

Antigène: LYPD3 (LY6/PLAUR Domain Containing 3 (LYPD3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LYPD3 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-LYPD3 anticorps

Épitope: AA 31-245

Fonction: LYPD3 Antibody / Ly6/PLAUR domain-containing protein 3

Purification: Antigen affinity purified

Immunogène: An E.coli-derived human recombinant protein (amino acids L31-E245) was used as the immunogen for the LYPD3 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the LYPD3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the LYPD3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur LYPD3

Antigène: LYPD3 (LY6/PLAUR Domain Containing 3 (LYPD3))

Autre désignation: LYPD3

Sujet: Ly6/PLAUR domain-containing protein 3 is a protein that in humans is encoded by the LYPD3 gene. Ly6 / PLAUR domain-containing protein 3, also known as GPI-anchored metastasis-associated protein C4.4A homolog, Matrigel-induced gene C4 protein, MIG-C4, and LYPD3, is a cell membrane protein that contains two UPAR/Ly6 domains. Human LYPD3 contains two UPAR/Ly6 domains. LYPD3 is expressed in the placenta, skin, and urothelium. It is found in suprabasal keratinocytes of chronic wounds. Weak expression of LYPD3 is found in the esophagus and peripheral blood mononuclear cells. It is found in the majority of primary and metastatic transitional cell carcinomas (TCCs) and as well in breast cancer tissues, but not in adjacent normal tissues. High expression of LYPD3 is found in the tumor component of some noninvasive superficial lesions and invasive and metastatic urothelial cancers. LYPD3 is up-regulated in migrating keratinocytes during epithelisation of incisional skin wounds. LYPD3 supports cell migration. It may be involved in urothelial cell-matrix interactions. It may also be involved in tumor progression.

UniProt: O95274