CD226 anticorps (AA 31-333)

N° du produit ABIN7873782

L’anticorps anti-CD226 Polyclonal Lapin est utilisé pour la détection de CD226 dans des échantillons de Souris et Rat. Il a été validé pour WB, FACS, ELISA et IHC (p).

Aperçu rapide pour CD226 anticorps (AA 31-333) (ABIN7873782)

Antigène: CD226

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD226 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CD226 anticorps

Épitope: AA 31-333

Fonction: Cd226 Antibody / Dnam-1

Purification: Antigen affinity purified

Immunogène: Recombinant mouse protein (amino acids E31-L333) was used as the immunogen for the Cd226 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Cd226 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Cd226 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur CD226

Antigène: CD226

Autre désignation: Cd226

Sujet: DNAM 1, also known as CD226, is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. DNAM 1 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. DNAM-1 is also expressed by a subset of CD3 positive thymocytes. This antibody is reported to inhibit T- and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells.

UniProt: Q8K4F0

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints