SCP2 anticorps (AA 33-547)

N° du produit ABIN7874006

Cet anticorps Lapin Polyclonal détecte spécifiquement SCP2 dans WB, ELISA et FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SCP2 anticorps (AA 33-547) (ABIN7874006)

Antigène: SCP2 (Sterol Carrier Protein 2 (SCP2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SCP2 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-SCP2 anticorps

Épitope: AA 33-547

Fonction: SCP2 Antibody / Sterol carrier protein 2

Purification: Immunogen affinity purified

Immunogène: E.coli-derived human SCP2 recombinant protein (Position: R33-L547) was used as the immunogen for the SCP2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the SCP2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the SCP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur SCP2

Antigène: SCP2 (Sterol Carrier Protein 2 (SCP2))

Autre désignation: SCP2

Sujet: SCP2 antibody detects Sterol carrier protein 2, encoded by the SCP2 gene. Sterol carrier protein 2 is a non-specific lipid transfer protein involved in intracellular lipid metabolism, peroxisomal function, and cholesterol trafficking. SCP2 antibody provides researchers with a valuable reagent for studying lipid transport, peroxisomal disorders, and cholesterol regulation.

Sterol carrier protein 2 plays a critical role in binding and transferring a wide range of lipids, including cholesterol, fatty acids, and phospholipids. Research using SCP2 antibody has shown that it localizes to peroxisomes, mitochondria, and the cytosol, where it helps mediate transport between organelles. By facilitating lipid shuttling, SCP2 contributes to membrane biosynthesis, signaling, and energy metabolism.

Studies with SCP2 antibody have revealed that the protein is synthesized as a multifunctional peroxisomal enzyme complex containing both thiolase activity and lipid transfer function. This dual nature allows SCP2 to integrate fatty acid oxidation with lipid transport, making it essential for peroxisomal physiology. Loss of SCP2 activity disrupts cholesterol homeostasis and leads to peroxisome-related disease phenotypes.

Dysregulation of Sterol carrier protein 2 has been associated with metabolic disease, cancer, and neurodegeneration. Research using SCP2 antibody has shown that reduced expression alters cholesterol trafficking, contributing to lipid storage disorders. Elevated expression has been observed in tumors, where SCP2 enhances membrane biosynthesis and supports proliferation. These findings highlight its dual role in normal physiology and disease pathology.

SCP2 antibody is widely applied in immunohistochemistry, western blotting, and immunofluorescence. Immunohistochemistry demonstrates expression in liver, adrenal gland, and brain, western blotting quantifies levels in cell lines and tissues, immunofluorescence reveals localization to peroxisomes and cytoplasm. These methods make SCP2 antibody indispensable for lipid transport research.

By providing validated SCP2 antibody reagents, NSJ Bioreagents supports studies into lipid metabolism, peroxisomal disorders, and disease. Detection of Sterol carrier protein 2 provides researchers with insight into how lipid transfer proteins influence cellular function and pathology.

UniProt: P22307

Pathways: C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process