SIM2 anticorps (AA 337-609)
Aperçu rapide pour SIM2 anticorps (AA 337-609) (ABIN7874056)
Antigène
Voir toutes SIM2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 337-609
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Fonction
- SIM2 Antibody / Single-minded homolog 2 / BHLHE15
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Purification
- Antigen affinity chromatography
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Immunogène
- An E.coli-derived human recombinant protein (amino acids Y337-R609) was used as the immunogen for the SIM2 antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the SIM2 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the SIM2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SIM2 (Single-Minded Homolog 2 (SIM2))
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Autre désignation
- SIM2
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Sujet
- Single-minded homolog 2 is a protein that in humans is encoded by the SIM2 gene. This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.
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UniProt
- Q14190
Antigène
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