ITGA8 anticorps (AA 347-964)

N° du produit ABIN7874121

L’anticorps anti-ITGA8 Polyclonal Lapin est utilisé pour la détection de ITGA8 dans des échantillons de Humain. Il a été validé pour WB, ELISA, FACS et IF.

Aperçu rapide pour ITGA8 anticorps (AA 347-964) (ABIN7874121)

Antigène: ITGA8 (Integrin alpha-8 (ITGA8))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITGA8 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Détail du produit anti-ITGA8 anticorps

Épitope: AA 347-964

Fonction: Integrin alpha 8 Antibody / ITGA8

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids E347-D964) was used as the immunogen for the Integrin alpha 8 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Integrin alpha 8 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Integrin alpha 8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur ITGA8

Antigène: ITGA8 (Integrin alpha-8 (ITGA8))

Autre désignation: Integrin alpha 8

Sujet: Integrin alpha-8 is a protein that in humans is encoded by the ITGA8 gene. Integrins are heterodimeric transmembrane receptor proteins that mediate numerous cellular processes including cell adhesion, cytoskeletal rearrangement, and activation of cell signaling pathways. Integrins are composed of alpha and beta subunits. This gene encodes the alpha 8 subunit of the heterodimeric integrin alpha8beta1 protein. The encoded protein is a single-pass type 1 membrane protein that contains multiple FG-GAP repeats. This repeat is predicted to fold into a beta propeller structure. This gene regulates the recruitment of mesenchymal cells into epithelial structures, mediates cell-cell interactions, and regulates neurite outgrowth of sensory and motor neurons. The integrin alpha8beta1 protein thus plays an important role in wound-healing and organogenesis. Mutations in this gene have been associated with renal hypodysplasia/aplasia-1 (RHDA1) and with several animal models of chronic kidney disease. Alternate splicing results in multiple transcript variants encoding distinct isoforms.

UniProt: P53708