P5CS anticorps (AA 35-204)

N° du produit ABIN7874156

Cet anticorps Lapin Polyclonal détecte spécifiquement P5CS dans IHC (p). Il présente une réactivité avec des échantillons de Poisson zèbre (Danio rerio).

Aperçu rapide pour P5CS anticorps (AA 35-204) (ABIN7874156)

Antigène: P5CS (ALDH18A1) (Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1))

Reactivité: Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp P5CS est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-P5CS anticorps

Épitope: AA 35-204

Fonction: Zebrafish Aldh18a1 Antibody / Glutamate 5-kinase / P5cs

Purification: Antigen affinity chromatography

Immunogène: An E.coli-derived zebrafish P5CS/ALDH18A1 recombinant protein (amino acids R35-A204) was used as the immunogen for the Zebrafish Aldh18a1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal dilution of the Zebrafish Aldh18a1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Zebrafish Aldh18a1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur P5CS

Antigène: P5CS (ALDH18A1) (Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1))

Autre désignation: Aldh18a1

Sujet: Delta-1-pyrroline-5-carboxylate synthetase (P5CS) is an enzyme that in humans is encoded by the ALDH18A1 gene. This gene is mapped to 10q24.1. This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene.

UniProt: A4IGC8