C1orf92 anticorps (AA 35-543)

N° du produit ABIN7874171

Cet anticorps Lapin Polyclonal détecte spécifiquement C1orf92 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour C1orf92 anticorps (AA 35-543) (ABIN7874171)

Antigène: C1orf92 (LRRC71) (Leucine Rich Repeat Containing 71 (LRRC71))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C1orf92 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-C1orf92 anticorps

Épitope: AA 35-543

Fonction: LRRC71 Antibody / Leucine-rich repeat-containing protein 71

Purification: Immunogen affinity purified

Immunogène: E.coli-derived human C1orf92/LRRC71 recombinant protein (Position: K35-D543) was used as the immunogen for the LRRC71 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the LRRC71 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the LRRC71 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur C1orf92

Antigène: C1orf92 (LRRC71) (Leucine Rich Repeat Containing 71 (LRRC71))

Autre désignation: LRRC71

Sujet: LRRC71 antibody detects Leucine-rich repeat-containing protein 71, a cytoplasmic and possibly nuclear protein characterized by multiple leucine-rich repeat motifs involved in protein-protein interactions. While the precise biological function of LRRC71 is still being elucidated, members of the leucine-rich repeat (LRR) family are commonly associated with cellular signaling, adhesion, and developmental regulation. The LRRC71 antibody is used in studies examining protein interaction networks, signal transduction pathways, and the potential roles of LRR proteins in neuronal and reproductive biology.

LRRC71 is encoded by the LRRC71 gene located on human chromosome 8q24.3. The protein contains tandem LRR motifs forming a horseshoe-shaped structure that facilitates binding to various partners, including receptors, kinases, and cytoskeletal proteins. Bioinformatic analyses suggest roles in cell differentiation and communication, possibly through modulation of receptor signaling. Expression profiling has revealed LRRC71 mRNA in multiple tissues, with enrichment in testis, brain, and epithelial organs, indicating possible participation in spermatogenesis and neurodevelopment.

Using the LRRC71 antibody, researchers can detect a band between 60-70 kilodaltons on western blot, corresponding to the predicted molecular weight of the protein. Immunostaining studies show cytoplasmic and perinuclear localization, consistent with a signaling or adaptor function. Although direct physiological functions remain under active investigation, related LRR family members are known to mediate receptor clustering and intracellular scaffolding, suggesting a conserved molecular role for LRRC71 in signal integration and cell organization.

Emerging data suggest LRRC71 may interact with intracellular components regulating calcium signaling or vesicular trafficking. Its predicted structural features imply involvement in membrane-proximal signaling complexes that respond to developmental or stress cues. Further investigation may also link LRRC71 to fertility regulation, as several LRR proteins participate in germ cell communication and acrosome formation. NSJ Bioreagents provides a validated LRRC71 antibody optimized for western blot, immunofluorescence, and immunohistochemistry applications, supporting research into LRR protein structure, signaling, and cellular differentiation.

UniProt: Q8N4P6