KRT14 anticorps (AA 351-472)

N° du produit ABIN7874235

L’anticorps anti-KRT14 Monoclonal Souris est utilisé pour la détection de KRT14 dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS et IHC (p).

Aperçu rapide pour KRT14 anticorps (AA 351-472) (ABIN7874235)

Antigène: KRT14 (Keratin 14 (KRT14))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KRT14 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: KRT14-2375

Détail du produit anti-KRT14 anticorps

Épitope: AA 351-472

Fonction: Cytokeratin 14 Antibody / KRT14

Purification: Protein G affinity chromatography

Immunogène: A recombinant human partial protein (amino acids 351-472) was used as the immunogen for this Cytokeratin 14 antibody.

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal dilution of the Cytokeratin 14 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Cytokeratin 14 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur KRT14

Antigène: KRT14 (Keratin 14 (KRT14))

Autre désignation: Cytokeratin 14

Sujet: Cytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors. Anti-CK14 is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore, this antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics, and in identifying metaplastic carcinomas of the breast.

UniProt: P02533