SPTA1 anticorps (AA 356-475)

N° du produit ABIN7874267

Cet anticorps Souris Monoclonal détecte spécifiquement SPTA1 dans WB, ELISA et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour SPTA1 anticorps (AA 356-475) (ABIN7874267)

Antigène: SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SPTA1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: SPTA1-1832

Détail du produit anti-SPTA1 anticorps

Épitope: AA 356-475

Fonction: Spectrin alpha 1 Antibody / SPTA1 (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: A portion of amino acids 356-475 from the human protein was used as the immunogen for the Spectrin alpha 1 antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the Spectrin alpha 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Spectrin alpha 1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur SPTA1

Antigène: SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))

Autre désignation: Spectrin alpha 1

Sujet: Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. Spectrins function as membrane organizers and stabilizers, composed of non-homologous and chains, which aggregate side-to-side in an anti-parallel fashion to form dimers, tetramers and higher polymers. Spectrin Ia and spectrin Ib are present in erythrocytes, whereas spectrin IIa (also designated fodrin alpha) and spectrin IIb (also designated fodrin beta) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function.

UniProt: P02549

Pathways: Regulation of Actin Filament Polymerization