INHBB anticorps (AA 369-397)

N° du produit ABIN7874377

Cet anticorps anti-INHBB Polyclonal Lapin (ABIN7874377) détecte spécifiquement INHBB dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour INHBB anticorps (AA 369-397) (ABIN7874377)

Antigène: INHBB (Inhibin, beta B (INHBB))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp INHBB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-INHBB anticorps

Épitope: AA 369-397

Fonction: Inhibin beta B chain Antibody / INHBB

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 369-397 from the human protein was used as the immunogen for the Inhibin beta B chain antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the Inhibin beta B chain antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Inhibin beta B chain antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur INHBB

Antigène: INHBB (Inhibin, beta B (INHBB))

Autre désignation: Inhibin beta B chain

Sujet: The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.

UniProt: P09529

Pathways: Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion