Cet anticorps Lapin Polyclonal détecte spécifiquement COX7A2L dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain et Souris.
COX7A2L
Reactivité: Humain, Souris
WB, IHC, ELISA
Hôte: Lapin
Polyclonal
PE
Indications d'application
The stated application concentrations are suggested starting points. Titration of the COX7A2L antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Aliquot the COX7A2L antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Antigène
COX7A2L
(Cytochrome C Oxidase Subunit VIIa Polypeptide 2 Like (COX7A2L))
Autre désignation
COX7A2L
Sujet
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen.