OB Cadherin anticorps (AA 371-796)
Aperçu rapide pour OB Cadherin anticorps (AA 371-796) (ABIN7874428)
Antigène
Voir toutes OB Cadherin (CDH11) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 371-796
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Fonction
- Cadherin 11 Antibody / CDH11 / OB-Cadherin
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Purification
- Affinity purified
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Immunogène
- A human recombinant partial protein (amino acids K371-S796) was used as the immunogen for the Cadherin 11 antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the Cadherin 11 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the Cadherin 11 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- OB Cadherin (CDH11) (Cadherin 11 (CDH11))
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Autre désignation
- Cadherin 11
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Sujet
- Cadherin-11, also called Osteoblast cadherin or OB Cadherin, is a protein that in humans is encoded by the CDH11 gene. This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.
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UniProt
- P55287
Antigène
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