PLK2 anticorps (AA 375-406)
Aperçu rapide pour PLK2 anticorps (AA 375-406) (ABIN7874461)
Antigène
Voir toutes PLK2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 375-406
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Fonction
- Polo-like kinase 2 Antibody / PLK2 / SNK
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Purification
- Antigen affinity purified
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Immunogène
- A portion of amino acids 375-406 from the human protein was used as the immunogen for the Polo-like kinase 2 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- The stated application concentrations are suggested starting points. Titration of the Polo-like kinase 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the Polo-like kinase 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- PLK2 (Polo-Like Kinase 2 (PLK2))
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Autre désignation
- Polo-like kinase 2
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Sujet
- Plks (polo-like kinases) encode serine/threonine kinases that are closely related to polo and CDC5, genes that are required for passage through mitosis in Drosophila and Saccharomyces, respectively. Polo-like kinases, which include Plk, Snk (for serum-inducible kinase, also designated Plk2) and Fnk (for FGF-inducible kinase, also designated Plk3 or PRK), play a role in cell proliferation. Plk protein accumulates in the cell during S and G2 phases of the cell cycle, and both protein content and catalytic activity peak at the onset of mitosis, followed by a rapid reduction after mitosis. Snk and Fnk are immediate-early response genes that are first expressed during G1 phase. SNK may play a role in the division of at least some cell types, such as fibroblasts, and could function in embryogenesis, wound healing or neoplasia SNK mRNA is rapidly induced in human lung fibroblasts upon reintroduction of serum following 36 hours of serum deprivation.
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UniProt
- Q9NYY3
Antigène
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