FTL anticorps (AA 38-165) (Biotin)

N° du produit ABIN7874494

Cet anticorps anti-FTL Monoclonal Souris conjugué à Biotin (Clone FTL-1386) (ABIN7874494) détecte spécifiquement FTL dans WB, ELISA et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour FTL anticorps (AA 38-165) (Biotin) (ABIN7874494)

Antigène: FTL (Ferritin, Light Polypeptide (FTL))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FTL est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: FTL-1386

Détail du produit anti-FTL anticorps (Biotin)

Épitope: AA 38-165

Fonction: FTL Antibody / Biotin Conjugate

Purification: Protein G affinity chromatography

Immunogène: A portion of amino acids 38-165 from the human protein was used as the immunogen for the FTL antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the FTL antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the FTL antibody at 2-8oC (up to one month) or aliquot and store at -20oC (longer term).

Détails sur FTL

Antigène: FTL (Ferritin, Light Polypeptide (FTL))

Autre désignation: FTL

Sujet: Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.

UniProt: P02792

Pathways: Transition Metal Ion Homeostasis