FTL anticorps (Light Chain)

N° du produit ABIN7874495

Cet anticorps Souris Monoclonal détecte spécifiquement FTL dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour FTL anticorps (Light Chain) (ABIN7874495)

Antigène: FTL (Ferritin, Light Polypeptide (FTL))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FTL est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: FTL-3100

Détail du produit anti-FTL anticorps

Épitope: AA 38-165, Light Chain

Fonction: FTL Antibody / Ferritin Light Chain (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: A portion of amino acids 38-165 from the human protein was used as the immunogen for the FTL antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the FTL antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the FTL antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur FTL

Antigène: FTL (Ferritin, Light Polypeptide (FTL))

Autre désignation: FTL

Sujet: Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyper-ferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.

UniProt: P02792

Pathways: Transition Metal Ion Homeostasis