DENND1B anticorps (AA 39-68)

N° du produit ABIN7874606

Cet anticorps Lapin Polyclonal détecte spécifiquement DENND1B dans WB, FACS et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour DENND1B anticorps (AA 39-68) (ABIN7874606)

Antigène: DENND1B (DENN/MADD Domain Containing 1B (DENND1B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DENND1B est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-DENND1B anticorps

Épitope: AA 39-68

Fonction: DENND1B Antibody

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 39-68 from the human protein was used as the immunogen for the DENND1B antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the DENND1B antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the DENND1B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur DENND1B

Antigène: DENND1B (DENN/MADD Domain Containing 1B (DENND1B))

Autre désignation: DENND1B

Sujet: Clathrin-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 and bind to clathrin and clathrin adaptor protein-2. Thus, connecdenns link RAB35 activation with the clathrin machinery.

UniProt: Q6P3S1