PDX1 anticorps (pan)

N° du produit ABIN7874661

L’anticorps anti-PDX1 Polyclonal Lapin est utilisé pour la détection de PDX1 dans des échantillons de Humain. Il a été validé pour WB, ELISA et FACS.

Aperçu rapide pour PDX1 anticorps (pan) (ABIN7874661)

Antigène: PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDX1 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-PDX1 anticorps

Épitope: AA 4-200, pan

Fonction: PDX1 Antibody / Pancreas/duodenum homeobox protein 1

Purification: Affinity purified

Immunogène: Recombinant human protein (amino acids E4-K200) was used as the immunogen for the PDX1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the PDX1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the PDX1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur PDX1

Antigène: PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

Autre désignation: PDX1

Sujet: PDX1 (pancreatic and duodenal homeobox 1), also known as insulin promoter factor 1, is a transcription factor in the ParaHox gene cluster. The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (IDDM), as well as maturity onset diabetes of the young type 4 (MODY4).

UniProt: P52945

Pathways: Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location