MADD anticorps (AA 4-335)

N° du produit ABIN7874673

L’anticorps anti-MADD Polyclonal Lapin est utilisé pour la détection de MADD dans des échantillons de Poisson zèbre (Danio rerio). Il a été validé pour WB.

Aperçu rapide pour MADD anticorps (AA 4-335) (ABIN7874673)

Antigène: MADD (MAP-Kinase Activating Death Domain (MADD))

Reactivité: Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MADD est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MADD anticorps

Épitope: AA 4-335

Fonction: Zebrafish Madd Antibody / MAP kinase-activating death domain protein

Purification: Antigen affinity chromatography

Immunogène: An E.coli-derived zebrafish Madd recombinant protein (amino acids K4-Y335) was used as the immunogen for the Zebrafish Madd antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal dilution of the Zebrafish Madd antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Zebrafish Madd antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur MADD

Antigène: MADD (MAP-Kinase Activating Death Domain (MADD))

Autre désignation: Madd

Sujet: MAP kinase-activating death domain protein is an enzyme that in humans is encoded by the MADD gene. Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene.

Pathways: Caspase Cascade in Apoptosis