HSD17B8 anticorps (AA 42-244)

N° du produit ABIN7874918

Cet anticorps Lapin Polyclonal détecte spécifiquement HSD17B8 dans WB, ELISA et FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour HSD17B8 anticorps (AA 42-244) (ABIN7874918)

Antigène: HSD17B8 (Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSD17B8 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-HSD17B8 anticorps

Épitope: AA 42-244

Fonction: HSD17B8 Antibody / 17-beta-hydroxysteroid dehydrogenase 8

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids D42-D244) was used as the immunogen for the HSD17B8 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the HSD17B8 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the HSD17B8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur HSD17B8

Antigène: HSD17B8 (Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8))

Autre désignation: HSD17B8

Sujet: Estradiol 17 beta-dehydrogenase 8, also called 17-beta-HSD 8 and Protein Ke6, is an enzyme that in humans is encoded by the HSD17B8 gene. In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined.

UniProt: Q92506

Pathways: Steroid Hormone Biosynthesis