CLPB anticorps (AA 438-707)

N° du produit ABIN7875000

L’anticorps anti-CLPB Polyclonal Lapin est utilisé pour la détection de CLPB dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IHC (p), FACS et IF.

Aperçu rapide pour CLPB anticorps (AA 438-707) (ABIN7875000)

Antigène: CLPB (ClpB Caseinolytic Peptidase B Homolog (CLPB))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CLPB est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (IF)

Détail du produit anti-CLPB anticorps

Épitope: AA 438-707

Fonction: CLPB Antibody / Caseinolytic peptidase B protein

Purification: Affinity purified

Immunogène: Recombinant human protein (amino acids Q438-I707) was used as the immunogen for the CLPB antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the CLPB antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the CLPB antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur CLPB

Antigène: CLPB (ClpB Caseinolytic Peptidase B Homolog (CLPB))

Autre désignation: CLPB

Sujet: This gene belongs to the ATP-ases associated with diverse cellular activities (AAA+) superfamily. Members of this superfamily form ring-shaped homo-hexamers and have highly conserved ATPase domains that are involved in various processes including DNA replication, protein degradation and reactivation of misfolded proteins. All members of this family hydrolyze ATP through their AAA+ domains and use the energy generated through ATP hydrolysis to exert mechanical force on their substrates. In addition to an AAA+ domain, the protein encoded by this gene contains a C-terminal D2 domain, which is characteristic of the AAA+ subfamily of Caseinolytic peptidases to which this protein belongs. It cooperates with Hsp70 in the disaggregation of protein aggregates. Allelic variants of this gene are associated with 3-methylglutaconic aciduria, which causes cataracts and neutropenia. Alternative splicing results in multiple transcript variants.

UniProt: Q9H078