PDIA3 anticorps (AA 446-475)
Aperçu rapide pour PDIA3 anticorps (AA 446-475) (ABIN7875047)
Antigène
Voir toutes PDIA3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 446-475
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Fonction
- Protein disulfide-isomerase A3 Antibody / PDIA3 / ERp57
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Purification
- Purified
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Immunogène
- A portion of amino acids 446-475 from the human protein was used as the immunogen for the Protein disulfide-isomerase A3 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- The stated application concentrations are suggested starting points. Titration of the Protein disulfide-isomerase A3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the Protein disulfide-isomerase A3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))
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Autre désignation
- Protein disulfide-isomerase A3
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Sujet
- PDIA3 is the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase, however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.
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UniProt
- P30101
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Pathways
- Maintenance of Protein Location, Protein targeting to Nucleus, Cell RedoxHomeostasis
Antigène
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