SMOX anticorps (AA 45-454)

N° du produit ABIN7875072

L’anticorps anti-SMOX Polyclonal Lapin est utilisé pour la détection de SMOX dans des échantillons de Humain, Souris et Rat. Il a été validé pour ELISA, WB, IF, FACS et IHC (p).

Aperçu rapide pour SMOX anticorps (AA 45-454) (ABIN7875072)

Antigène: SMOX (Spermine Oxidase (SMOX))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMOX est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-SMOX anticorps

Épitope: AA 45-454

Fonction: PAO-1 Antibody / Polyamine oxidase 1 / SMOX

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids E45-Q454) was used as the immunogen for the PAO-1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the PAO-1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the PAO-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur SMOX

Antigène: SMOX (Spermine Oxidase (SMOX))

Autre désignation: PAO-1

Sujet: Spermine oxidase, also called Polyamine oxidase 1 (PAO-1), is an enzyme that in humans is encoded by the SMOX gene. Polyamines are ubiquitous polycationic alkylamines which include spermine, spermidine, putrescine, and agmatine. These molecules participate in a broad range of cellular functions which include cell cycle modulation, scavenging reactive oxygen species, and the control of gene expression. These molecules also play important roles in neurotransmission through their regulation of cell-surface receptor activity, involvement in intracellular signalling pathways, and their putative roles as neurotransmitters. This gene encodes an FAD-containing enzyme that catalyzes the oxidation of spermine to spermadine and secondarily produces hydrogen peroxide. Multiple transcript variants encoding different isoenzymes have been identified for this gene, some of which have failed to demonstrate significant oxidase activity on natural polyamine substrates. The characterized isoenzymes have distinctive biochemical characteristics and substrate specificities, suggesting the existence of additional levels of complexity in polyamine catabolism.

UniProt: Q9NWM0