ACPL2 anticorps (AA 45-459)
Aperçu rapide pour ACPL2 anticorps (AA 45-459) (ABIN7875074)
Antigène
Voir toutes ACPL2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 45-459
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Fonction
- PXYLP1 Antibody / 2-Phosphoxylose phosphatase 1
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Purification
- Antigen affinity purified
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Immunogène
- An E.coli-derived human recombinant protein (amino acids K45-D459) was used as the immunogen for the PXYLP1 antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the PXYLP1 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the PXYLP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- ACPL2 (Acid Phosphatase-Like 2 (ACPL2))
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Autre désignation
- PXYLP1
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Sujet
- PXYLP1 dephosphorylates the xylose (xyl) residue in the glycosaminoglycan (GAG)-protein linkage region of proteoglycans, which is required for biosynthetic maturation of the linkage region. Responsible for the 2-O-dephosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature glycosaminoglycan (GAG) chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG-protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1-O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases. Xylose 2-O-dephosphorylation during completion of linkage region formation is a prerequisite for the initiation and efficient elongation of the repeating disaccharide region of GAG chains.
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UniProt
- Q8TE99
Antigène
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