Cet anticorps Lapin Polyclonal détecte spécifiquement ACPL2 dans WB, ELISA et FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.
ACPL2
Reactivité: Humain, Souris, Rat
WB, IHC (p)
Hôte: Lapin
Polyclonal
HRP
Indications d'application
Optimal dilution of the PXYLP1 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock
4 °C,-20 °C
Stockage commentaire
After reconstitution, the PXYLP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Antigène
ACPL2
(Acid Phosphatase-Like 2 (ACPL2))
Autre désignation
PXYLP1
Sujet
PXYLP1 dephosphorylates the xylose (xyl) residue in the glycosaminoglycan (GAG)-protein linkage region of proteoglycans, which is required for biosynthetic maturation of the linkage region. Responsible for the 2-O-dephosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature glycosaminoglycan (GAG) chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG-protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1-O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases. Xylose 2-O-dephosphorylation during completion of linkage region formation is a prerequisite for the initiation and efficient elongation of the repeating disaccharide region of GAG chains.