Dynamin 1-Like anticorps (AA 452-736)

N° du produit ABIN7875098

Cet anticorps Lapin Polyclonal détecte spécifiquement Dynamin 1-Like dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour Dynamin 1-Like anticorps (AA 452-736) (ABIN7875098)

Antigène: Dynamin 1-Like (DNM1L)

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Dynamin 1-Like est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Dynamin 1-Like anticorps

Épitope: AA 452-736

Fonction: Dynamin-1-like protein Antibody / DNM1L / DRP1

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids Q452-W736) was used as the immunogen for the Dynamin-1-like protein antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Dynamin-1-like protein antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Dynamin-1-like protein antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Dynamin 1-Like

Antigène: Dynamin 1-Like (DNM1L)

Autre désignation: Dynamin-1-like protein

Sujet: Dynamin-1-like protein is a GTPase that regulates mitochondrial fission. In humans, dynamin-1-like protein, which is typically referred to as dynamin-related protein 1 (Drp1), is encoded by the DNM1L gene. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: O00429