Seryl-tRNA Synthetase (SARS) (AA 46-518) anticorps

N° du produit ABIN7875122

Cet anticorps Lapin Polyclonal détecte spécifiquement Seryl-tRNA Synthetase dans WB, ELISA, IF et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Seryl-tRNA Synthetase (SARS) (AA 46-518) anticorps (ABIN7875122)

Antigène: Seryl-tRNA Synthetase (SARS)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit

Épitope: AA 46-518

Fonction: SerRS Antibody / Seryl-tRNA synthetase / SARS2

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids E46-S518) was used as the immunogen for the SerRS antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the SerRS antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the SerRS antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détail du antigène

Antigène: Seryl-tRNA Synthetase (SARS)

Autre désignation: SerRS

Sujet: Seryl-tRNA synthetase, mitochondrial is an enzyme that in humans is encoded by the SARS2 gene. This gene encodes the mitochondrial seryl-tRNA synthethase precursor, a member of the class II tRNA synthetase family. The mature enzyme catalyzes the ligation of Serine to tRNA(Ser) and participates in the biosynthesis of selenocysteinyl-tRNA(sec) in mitochondria. The enzyme contains an N-terminal tRNA binding domain and a core catalytic domain. It functions in a homodimeric form, which is stabilized by tRNA binding. This gene is regulated by a bidirectional promoter that also controls the expression of mitochondrial ribosomal protein S12. Both genes are within the critical interval for the autosomal dominant deafness locus DFNA4 and might be linked to this disease. Multiple transcript variants encoding different isoforms have been identified for this gene.

UniProt: Q9NP81