RGMB anticorps (AA 47-404)

N° du produit ABIN7875162

L’anticorps anti-RGMB Polyclonal Lapin est utilisé pour la détection de RGMB dans des échantillons de Humain et Souris. Il a été validé pour WB, ELISA et FACS.

Aperçu rapide pour RGMB anticorps (AA 47-404) (ABIN7875162)

Antigène: RGMB (RGM Domain Family, Member B (RGMB))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RGMB est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-RGMB anticorps

Épitope: AA 47-404

Fonction: RGMB Antibody / Repulsive Guidance Molecule B

Purification: Affinity purified

Immunogène: Recombinant human protein (amino acids D47-R404) was used as the immunogen for the RGMB antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the RGMB antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the RGMB antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur RGMB

Antigène: RGMB (RGM Domain Family, Member B (RGMB))

Autre désignation: RGMB

Sujet: Repulsive guidance molecule B (RGMb), also known as DRAGON (DRG11-responsive axonal guidance and outgrowth of neurite), is a bone morphogenetic protein (BMP) co-receptor of the repulsive guidance molecule family. In humans this protein is encoded by the RGMB gene. RGMB is a glycosylphosphatidylinositol (GPI)-anchored member of the repulsive guidance molecule family (see also RGMA and RGMC) and contributes to the patterning of the developing nervous system. There is a potential association between RGMs and cancer bone metastasis, as RGMs coordinate bone morphogenetic protein (BMP) signaling. RGMB may act as a negative regulator in vitro in breast cancer and prostate cancer through BMP signalling. Furthermore, aberrant expression of RGMs was indicated in breast cancer. The perturbed expression was associated with disease progression and poor prognosis.

UniProt: Q6NW40