MAPK8IP1 anticorps (AA 470-498)
Aperçu rapide pour MAPK8IP1 anticorps (AA 470-498) (ABIN7875168)
Antigène
Voir toutes MAPK8IP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 470-498
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Fonction
- MAPK8IP1 Antibody / JIP1
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Purification
- Antigen affinity purified
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Immunogène
- A portion of amino acids 470-498 from the human protein was used as the immunogen for the MAPK8IP1 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- The stated application concentrations are suggested starting points. Titration of the MAPK8IP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the MAPK8IP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- MAPK8IP1 (Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1))
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Autre désignation
- MAPK8IP1
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Sujet
- JIP1 is a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2.
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UniProt
- Q9UQF2
Antigène
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