L’anticorps anti-MAPK8IP1 Polyclonal Lapin est utilisé pour la détection de MAPK8IP1 dans des échantillons de Humain. Il a été validé pour WB, IF, IHC (p) et FACS.
The stated application concentrations are suggested starting points. Titration of the MAPK8IP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Aliquot the MAPK8IP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Antigène
MAPK8IP1
(Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1))
Autre désignation
MAPK8IP1
Sujet
JIP1 is a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2.