BIRC6 anticorps (AA 4810-4844)

N° du produit ABIN7875225

L’anticorps anti-BIRC6 Polyclonal Lapin est utilisé pour la détection de BIRC6 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour BIRC6 anticorps (AA 4810-4844) (ABIN7875225)

Antigène: BIRC6 (Baculoviral IAP Repeat-Containing 6 (BIRC6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BIRC6 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-BIRC6 anticorps

Épitope: AA 4810-4844

Fonction: BIRC6 Antibody (C-Terminal Region)

Purification: Antigen affinity

Immunogène: A portion of amino acids 4810-4844 from human BIRC6 was used as the immunogen for the BIRC6 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the BIRC6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the BIRC6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur BIRC6

Antigène: BIRC6 (Baculoviral IAP Repeat-Containing 6 (BIRC6))

Autre désignation: BIRC6

Sujet: Baculoviral IAP repeat-containing protein 6 / APOLLON is an anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase. Its tragets include CASP9 and DIABLO/SMAC. Acts as an inhibitor of CASP3, CASP7 and CASP9. Important regulator for the final stages of cytokinesis. Crucial for normal vesicle targeting to the site of abscission, but also for the integrity of the midbody and the midbody ring, and its striking ubiquitin modification. [UniProt]

UniProt: Q9NR09