Mps1 anticorps (AA 487-821)

N° du produit ABIN7875232

Cet anticorps anti-Mps1 Polyclonal Lapin (ABIN7875232) détecte spécifiquement Mps1 dans WB, ELISA, IF, IHC (p) et FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Mps1 anticorps (AA 487-821) (ABIN7875232)

Antigène: Mps1 (TTK)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Mps1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-Mps1 anticorps

Épitope: AA 487-821

Fonction: TTK Antibody

Purification: Affinity purified

Immunogène: Recombinant human protein (amino acids Q487-S821) was used as the immunogen for the TTK antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the TTK antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the TTK antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Mps1

Antigène: Mps1 (TTK)

Autre désignation: TTK

Sujet: Dual specificity protein kinase TTK is a protein that in humans is encoded by the TTK gene. This gene is mapped to 6q14.1. This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants.

UniProt: P33981