TNK2 anticorps (AA 491-1038)
Aperçu rapide pour TNK2 anticorps (AA 491-1038) (ABIN7875263)
Antigène
Voir toutes TNK2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 491-1038
-
Fonction
- Activated CDC42 kinase 1 Antibody / ACK1
-
Purification
- Antigen affinity purified
-
Immunogène
- E. coli-derived recombinant human protein (amino acids M491-R1038) was used as the immunogen for the Activated CDC42 kinase 1 antibody.
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal dilution of the Activated CDC42 kinase 1 antibody should be determined by the researcher.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- After reconstitution, the Activated CDC42 kinase 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))
-
Autre désignation
- Activated CDC42 kinase 1
-
Sujet
- Activated CDC42 kinase 1, also known as ACK1, is an enzyme that in humans is encoded by the TNK2 gene. This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.
-
UniProt
- Q07912
Antigène
-