CEACAM1 anticorps (AA 50-250)

N° du produit ABIN7875339

L’anticorps anti-CEACAM1 Monoclonal Souris est utilisé pour la détection de CEACAM1 dans des échantillons de Humain. Il a été validé pour WB et IHC (p).

Aperçu rapide pour CEACAM1 anticorps (AA 50-250) (ABIN7875339)

Antigène: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CEACAM1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CEACAM1-12661

Détail du produit anti-CEACAM1 anticorps

Épitope: AA 50-250

Fonction: CD66a Antibody / CEACAM1 / BGP-1

Purification: Protein G affinity

Immunogène: A portion of amino acids 50-250 from human CEACAM1 protein was used as the immunogen for the CD66a antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the CD66a antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the CD66a antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur CEACAM1

Antigène: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Autre désignation: CD66a

Sujet: Carcinoembryonic antigen (CEA) is one of the most commonly used tumor markers in serum immunoassay determinations of carcinoma. Members of the CEACAM (carcinoembryonic antigen-related cell adhesion molecule) family contain a single N domain, with structural homology to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constantlike A and/or B domains. CEACAM1 (carcinoembryonic antigen-related cell adhesion molecule 1), also known as BGP or BGP1, is a 526 amino acid protein that exists as seven alternatively spliced isoforms, some of which localize to the cell membranes, while others are secreted. One of several members of the CEACAM family, CEACAM1 contains one Ig-like V-type domain and three Ig-like C2-type domains and is thought to play a role in a variety of cellular activities, including angiogenesis, apoptosis, arrangement of tissue threedimensional structure and modulation of innate and adaptive immune responses. Additionally, CEACAM1 is underexpressed in colorectal cancers, suggesting a role in tumor suppression.

UniProt: P13688