CEACAM1 anticorps (AA 50-250)

N° du produit ABIN7875342

L’anticorps anti-CEACAM1 Monoclonal Souris est utilisé pour la détection de CEACAM1 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour CEACAM1 anticorps (AA 50-250) (ABIN7875342)

Antigène: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CEACAM1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: CEACAM1-4837

Détail du produit anti-CEACAM1 anticorps

Épitope: AA 50-250

Fonction: Carcinoembryonic antigen-related cell adhesion molecule 1 Antibody / CEACAM1 / BGP-1 (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: A recombinant fragment (within amino acids 50-250) of human CEACAM1 protein was used as the immunogen for the Carcinoembryonic antigen-related cell adhesion molecule 1 antibody.

Isotype: IgG2, kappa

Information d'application

Indications d'application: Optimal dilution of the Carcinoembryonic antigen-related cell adhesion molecule 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the Carcinoembryonic antigen-related cell adhesion molecule 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur CEACAM1

Antigène: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Autre désignation: Carcinoembryonic antigen-related cell adhesion molecule 1

Sujet: Carcinoembryonic antigen (CEA) is one of the most commonly used tumor markers in serum immunoassay determinations of carcinoma. Members of the CEACAM (carcinoembryonic antigen-related cell adhesion molecule) family contain a single N domain, with structural homology to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constantlike A and/or B domains. CEACAM1 (carcinoembryonic antigen-related cell adhesion molecule 1), also known as BGP or BGP1, is a 526 amino acid protein that exists as seven alternatively spliced isoforms, some of which localize to the cell membranes, while others are secreted. One of several members of the CEACAM family, CEACAM1 contains one Ig-like V-type domain and three Ig-like C2-type domains and is thought to play a role in a variety of cellular activities, including angiogenesis, apoptosis, arrangement of tissue threedimensional structure and modulation of innate and adaptive immune responses. Additionally, CEACAM1 is underexpressed in colorectal cancers, suggesting a role in tumor suppression.

UniProt: P13688