CEACAM1 anticorps (AA 50-250)

N° du produit ABIN7875344

Cet anticorps Souris Monoclonal détecte spécifiquement CEACAM1 dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour CEACAM1 anticorps (AA 50-250) (ABIN7875344)

Antigène: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CEACAM1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: CEACAM1-4843

Détail du produit anti-CEACAM1 anticorps

Épitope: AA 50-250

Fonction: BGP-1 Antibody / CEACAM1 (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein sequence (within amino acids 50-250) from the human protein was used as the immunogen for the BGP-1 antibody.

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal dilution of the BGP-1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the BGP-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur CEACAM1

Antigène: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Autre désignation: BGP-1

Sujet: Carcinoembryonic antigen (CEA) is one of the most commonly used tumor markers in serum immunoassay determinations of carcinoma. Members of the CEACAM (carcinoembryonic antigen-related cell adhesion molecule) family contain a single N domain, with structural homology to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. CEACAM1 (carcinoembryonic antigen-related cell adhesion molecule 1), also known as BGP or BGP1 (Biliary glycoprotein 1), is a 526 amino acid protein that exists as seven alternatively spliced isoforms, some of which localize to the cell membranes, while others are secreted. One of several members of the CEACAM family, CEACAM1 contains one Ig-like V-type domain and three Ig-like C2-type domains and is thought to play a role in a variety of cellular activities, including angiogenesis, apoptosis, arrangement of tissue three dimensional structure and modulation of innate and adaptive immune responses. Additionally, CEACAM1 is under-expressed in colorectal cancers, suggesting a role in tumor suppression.

UniProt: P13688