CD207 anticorps (AA 50-250)

N° du produit ABIN7875353

Cet anticorps Souris Monoclonal détecte spécifiquement CD207 dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour CD207 anticorps (AA 50-250) (ABIN7875353)

Antigène: CD207 (CD207 Molecule, Langerin (CD207))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD207 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: LGRN-7357

Détail du produit anti-CD207 anticorps

Épitope: AA 50-250

Fonction: Langerin Antibody / CD207

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein sequence (within amino acids 50-250) from the human protein was used as the immunogen for the Langerin antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Langerin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Langerin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur CD207

Antigène: CD207 (CD207 Molecule, Langerin (CD207))

Autre désignation: Langerin

Sujet: Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2+-dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein.

UniProt: Q9UJ71