Recombinant GLUL anticorps (AA 50-250)

N° du produit ABIN7875376

Cet anticorps anti-GLUL Monoclonal Lapin (Clone GLUL-8517R) (ABIN7875376) détecte spécifiquement GLUL dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant GLUL anticorps (AA 50-250) (ABIN7875376)

Antigène: GLUL (Glutamate-Ammonia Ligase (GLUL))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp GLUL est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: GLUL-8517R

Détail du produit anti-GLUL anticorps

Épitope: AA 50-250

Fonction: GLUL Antibody / Glutamine Synthetase

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein sequence (within amino acids 50-250) from the human protein was used as the immunogen for the GLUL antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the GLUL antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the GLUL antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur GLUL

Antigène: GLUL (Glutamate-Ammonia Ligase (GLUL))

Autre désignation: GLUL

Sujet: Glutamine synthetase (Gl Syn) forms a homo-octamer that serves as a catalyst for the amination of glutamic acid to form glutamine. This enzyme is a marker for astrocytes, which serve as the primary site of conversion of glutamic acid to glutamine in the brain. Induction of glutamine synthetase is seen upon astrocyte cell contact with neurons. Elevated expression of glutamine synthetase in glial cells has been shown to protect neurons from degeneration due to excess glutamate. Glutamine synthetase is also present in the liver and is involved in nitrogen homeostasis. Overexpression of glutamine synthetase has been shown in primary liver cancers, indicating a potential role for glutamine synthetase in hepatocyte transformation.

UniProt: P15104

Pathways: Positive Regulation of Peptide Hormone Secretion