GLN1 anticorps (AA 50-250)

N° du produit ABIN7875378

L’anticorps anti-GLN1 Monoclonal Souris est utilisé pour la détection de GLN1 dans des échantillons de Humain. Il a été validé pour WB et IHC (p).

Aperçu rapide pour GLN1 anticorps (AA 50-250) (ABIN7875378)

Antigène: GLN1 (Glutamine Synthetase (GLN1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GLN1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: GLUL-6599

Détail du produit anti-GLN1 anticorps

Épitope: AA 50-250

Fonction: Glutamine Synthetase Antibody / GLUL

Purification: Protein A/G affinity

Immunogène: A portion of amino acids 50-250 was used as the immunogen for the GLUL antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the GLUL antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the GLUL antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur GLN1

Antigène: GLN1 (Glutamine Synthetase (GLN1))

Autre désignation: Glutamine Synthetase

Sujet: Glutamine synthetase (GlSyn) forms a homo-octamer that serves as a catalyst for the amination of glutamic acid to form glutamine. This enzyme is a marker for astrocytes, which serve as the primary site of conversion of glutamic acid to glutamine in the brain. Induction of glutamine synthetase is seen upon astrocyte cell contact with neurons. Elevated expression of glutamine synthetase in glial cells has been shown to protect neurons from degeneration due to excess glutamate. Glutamine synthetase is also present in the liver and is involved in nitrogen homeostasis. Overexpression of glutamine synthetase has been shown in primary liver cancers, indicating a potential role for glutamine synthetase in hepatocyte transformation.

UniProt: P15104

Pathways: Positive Regulation of Peptide Hormone Secretion